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Microbiology

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Gram Positive Cocci

Question
63 out of 78
 

Virulence of Pneumococci is due to:



A Capsular Polysacchride
B Nucleoprotein

C Carbohydrate antigen
D All of the above

Ans. A Capsular Polysacchride

Capsular Polysaccharide

The most important antigen of the pneumococcus is the type specific capsular polysaccharide. As this polysaccharide diffuses into the culture medium or infective exudates and tissue, it is also called the ‘specific soluble substance (SSS)’. Pneumococci are classified into more than 85 capsular types based on the antigenic nature of the capsular polysaccharide

a. The virulence of the pneumocci depends on its capsule and the production of a toxin called pneumolysin. The Capsular Polysaccharide because of its acidic and hydrophilic properties protects the cocci from phagocytosis.

b. Capsulated pneumococci are not effectively phagocytosed efficiently in fluid media or exudates. They are, however, susceptible to ‘surface phagocytosis’, being engulfed against a firm surface, such as fibrin clot or epithelium

c. Nucleoprotein is an antigen situated deep inside the cell and is species specific

d. Somatic ‘C’ Carbohydrate antigen is species specific

Gram Positive Cocci Flashcard List

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