Vitamins, Harmones and Hemoglobin
Vitamin A intoxication causes injury to(AIIMS May 2007)
Excess of vitamin A can lead to rupture of lysosomal membranes.
Clinical manifestations of hypervitaminosis:
a. Headache Vomiting
c. There are signs of raised intra-cranial tension including bulging of anterior fontanelle and / or papilledema-a syndrome known as pseudotumor cerebri.
d. Chronic toxication with large doses results in anorexia, dry itchy skin, weight loss, painful extremities, sparse hair, hepatosplenomegaly,
e. hypoplastic anemia and benign intracranial hypertension.
f. Also note: Carotenoids donot cause toxicity, except a reversible yellow colour of the skin.