When transfer factor is given as treatment, it results in: NEET13
|A||natural active immunity|
|B||artificial active immunity|
|C||artificial passive immunity|
Transfer factor is a highly potent extract from leucocytes.
It is a low molecular weight substance, resistant to trypsin, DNAse, RNAse and freeze-thawing. It is inactivated at 56o C in 30 minutes.
Chemically it appears to be a polypeptide-polynucleotide and is not antigenic.
It has the ability to transfer cell-mediated immunity in the recipient to those antigens to which the donor is sensitive.
The mechanism of action of the TF is not known. It could be an informational molecule capable of inducing antigenically uncommitted lymphocytes to produce antigen-specific receptors.