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Medicine

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Endocrine

Question
19 out of 21
 

Which adipokine reduces in insulin resistance (PNQ)



A Leptin
B TNF alpha

C Resistin
D All of the above

Ans. A

Leptin

Recent advances in Pathology of Type II diabetes (PNQ)

1). Genes for type II diabetics that cause the insulin resistance and the beta cell failure- a gene on chromosome 2 encoding a cysteine protease, calpain –10, has been reported in some patient.

2). Several adipokines, secreted by fat cells, can affect insulin Action.

Example of adipokines

1). Leptin

2). Adiponectin

3). TNFα

4). Resistin

Extra Edge:

1). Adipokines which reduce insulin resistance –

a. Leptin b. Adiponectin.

2). Adipokines which increase insulin resistance –

a. TNF-alpha b. Resistin

Endocrine Flashcard List

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