Which cell surface marker is required for lysis of IgG-coated target cells (antibody-dependent, cell-mediated cytotoxicity) by natural killer cells?
The marker by which NK cell attaches to the Fc part of antibody is CD16. markers used for identification of NK cells are CD16 and 56. NK cells are the part of innate immune response and have anti-viral and anti-tumor action. NK cells are also called as large granular lymphocytes (LGL).