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Medicine

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Endocrine

Question
13 out of 15
 

Which drug is used for medical adrenalectomy? (PNQ)



A Metyrapone
B Ketoconazole

C Trilostane
D All of the above

Ans. D

All of the above

Table - Treatment Modalities for Patients with Adrenal Hyperplasia Secondary to Pituitary ACTH Hypersecretion

(Ref. Hari-18th ed., Pg- 2948)

1). Treatments to reduce pituitary ACTH production

a. Transsphenoidal resection of microadenoma

b. Radiation therapy

2). Treatments to reduce or eliminate adrenocortical cortisol secretion

a. Bilateral adrenalectomy

b. Medical adrenalectomy:- i.e. Drugs used to reduce steroid synthesis.

i. Metyrapone

ii. Mitotane

iii. Aminoglutethimide

iv. Ketoconazole

v. Mifepristone

vi. Trilostane

vii. Cyproheptadine

viii. Etomidate. (Ref. Hari-18th ed., Pg- 2899)


Extra Edge
: Mifepristone is CI is pregnancy because it causes abortion, so also used for abortion.

Endocrine Flashcard List

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