Which is incorrectly matched
|A||Phenytoin - cleft lip and palate|
|C||Valproate - neural tube defect|
|D||ACE I- hyperkalemia|
a. Zidovudine is routinely prescribed in pregnancy without clinically significant evidence of cardiomyopathy. Other adverse outcomes are correctly matched. Zidovudine can cause skeletal muscle myopathy.
b. A muscle biopsy can differentiate between zidovudine induced myopathy from myopathy induced by HIV infection
Side effects of other RTIs (Most common drugs causing)
· Anemia: Zidovudine
· Neutropenia: Zidovudine and Didanosine
· Lipoatrophy: Stavudine
· Neuropathy: Zalcitabine/didanosine
· Clopidogrel and ticlopidine are the two antiplatelet drugs, which are prodrugs.