Loading....
Coupon Accepted Successfully!

Medicine

Open Flashcards

Endocrine

Question
6 out of 21
 

Which is not a feature of type II DM (LQ)



A Obesity

B Positive family history

C Autoimmune disorder

D Insulin Resistance

Ans. C

Autoimmune disorder

Features that suggest Type - 2 DM

1). Patient has over Weight Q

2). No autoantibodies Q

3). Ketosis is uncommon. Non ketotic hyper osmolar coma is common. Q

4). Family history strongly positive but not always positive.

5). Insulin resistance is the main cause Q

6). Serum insulin levels are very high ( hyper insulinemia ) Q

7). Treatment include weight loss, oral drugs & insulin Q

Extra Edge: Low serum insulin is not a feature of type II diabetes or it is a very late feature

Pathogenesis of Type II diabetes-

Insulin resistance occurs due to.

1). Impaired insulin secretion 2). Peripheral insulin resistance 3). Excessive hepatic glucose production

Differences between different types of Diabetes Mellitus –

Type 1 DM Type 2 DM

1). Age at onset - usually young Adults

2). HLA association DR3, DR4 No HLA association

3). Body weight- Lean & thin Obese

4). Family h/o - May or may not be there Strongly +ve (but not always positive)

5). Presentation - Usually (Abrupt) Gradual or asymptomatic

6). Insulin requirement Absolute, but drugs like AGI given, OHA, later insulin.

7). Serum insulin level- Low High

8). Etiology Autoimmune, Insulin resistance, impaired insulin secretion

Endocrine Flashcard List

21 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)