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Medicine

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Hematology

Question
2 out of 3
 

Which is the most common cytogenetic abnormality in adult myelodysplastic syndrome (MDS)? (PGI Nov2011)



A Trisomy 8
B 20q-

C 5q-
D Monosomy 7

Ans. C

5q-

Cytogenetic Abnormalities in MDS: Facts to Remember

1. Monosomy 7 is the most frequent cytogenetic abnormality in children.

2. Deletion 5q (5q-) is the most frequent cytogenetic abnormality in adults.

3. Trisomy 8 is the most frequent trisomy.