Which is the most common joint involved in pseudogout? (AIPG 02)
Pseudogout CPPD Deposition disease (AIIMS Nov 09) (Ref: H-18th edition, Pg-2839)
The deposition of CPPD (Calcium Pyrophosphate Dihydrate ) crystals in articular tissues is most common in the elderly.
Conditions Associated with Calcium Pyrophosphate Dihydrate Disease (Ref: H-18th edition, Table-332.2)
2. Disease-associated (4H)
a. Primary Hyperparathyroidism b. Hemochromatosis (AIPG 2006)
c. Hypophosphatasia d. Hypomagnesemia
e. Chronic gout
3. Post meniscectomy
Extra Edge: The knee is the joint most frequently affected in CPPD arthropathy (Large joints).
1. Calcium pyrophosphate dihydrate crystals, as seen in a fresh preparation of synovial fluid, illustrate rectangular, rod-shaped, and rhomboid weakly positive birefringent crystals
2. Meniscal calcification is a important diagnostic feature of CPPD.
1. NSAIDs 2. By intraarticular glucocorticoid injection