Thyroid & Adrenal
Which is true about hyperthyroidism?
|A||Goitre in 5 percent of population is endemic goitre|
|B||Thyroid storm, the clinical features are primarily due to increased thyroxine.|
|C||Most colid goiters are hyperthyroid|
|D||Polymorphic lymphocytosis is found|
(Option B). Pathophysiology is incompletely understood. Interestingly, serum free T4 concentrations were higher in patients with thyroid storm than in those with uncomplicated thyrotoxicosis, while serum total T4 levels did not differ in the two groups , suggesting that events like infections may decrease serum binding of T4 and cause a greater increase in free T4 responsible for storm occurrence.
In general endemic goiter would be considered to exist when more than 5% of an adolescent or preadolescent group have grade 1 goiter or when more than 30% are assigned to grade Ob or above.
The following classification scheme has been found satisfactory by many observers in assessing the prevalence of abnormal thyroids:
a. Grade Oa,thyroid not palpable, or if palpable not larger than normal;
b. Grade Ob,thyroid distinctly palpable but usually not visible with the head in a normal or raised position;
c. Grade 1,thyroid easily palpable and visible with the head in a normal position;
d. Grade 2,Thyroid easily visible.
e. Grade 3, goiter visible at a distance;
f. Grade 4,monstrous goiters.