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Pharmacology

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Analgesics

Question
14 out of 33
 

Which of the following is least narcotic (LQ)



A Morphine

B Fentanyl

C Diacetyl morphine

D Papaverine

Ans. D Papaverine (Ref: BG Katzung, pp-531, 11th Edition, 2009)

a. Papaverine is one of the product of juice of poppy plant and is deprived of narcotic property.

b. The drug is used most commonly as a penile vasodilator. It is the drug of choice for impotent patient with spinal cord injury.

c. However, repeated injections should be avoided as that may lead to penile fibrosis. Heroin is diacetylmorphine and is synthetic a prodrug of morphine with high abuse potential.

d. Codeine is a weak partial agonist of mu receptors while morphine is the main alkaloid obtained from juice of poppy plant.

e. Codeine is commonly used as an antidiarroheal, anti-cough medication. However drug of choice for suppression of cough on routine basis is dextromethorphan, a synthetic opioid with NMDA antagonist action.

f. It must be noted that cough should be dry. Productive cough should not be suppresseD.

Analgesics Flashcard List

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