Amino Acids, Proteins and Porphyrins
Which of the following is required for transfer of amino group? (AIPG 2011)
Aminotransferase (transaminase) reactions form:
a. Pyruvate from alanine,
b. Oxaloacetate from aspartate, and
c. α-ketoglutarate from glutamate.
Because these reactions are reversible, the cycle also serves as a source of carbon skeletons for the synthesis of these amino acids.
Other amino acids contribute to gluconeogenesis because their carbon skeletons give rise to citric acid cycle intermediates.
a. Alanine, cysteine, glycine, hydroxyproline, serine, threonine, and tryptophan yield pyruvate;
b. Arginine, histidine, glutamine, and proline yield α-ketoglutarate;
c. Isoleucine, methionine, and valine yield succinyl-CoA; and
d. Tyrosine and phenylalanine yield fumarate.