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Pathology

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Cell Injury

Question
18 out of 32
 

Which of the following is an antiapoptotic gene? (LQ)



A C-myc
B P 53
C Bcl-2
D Bax

Ans. C Bcl-2

Anti apoptotic proteins = Bcl-2, Bcl-XL

Proapoptotic protein = Bax, Bad

Bcl-2 has direct action on mitochondria to prevent increased permeability and by effects mediated by interactions with other proteins.

Extra Edge: Annexin V as marker for apoptotic cell membrane having phosphatidylserine on the cell interior.

Cell Injury Flashcard List

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