Which of the following is an antiapoptotic gene? (LQ)
Anti apoptotic proteins = Bcl-2, Bcl-XL
Proapoptotic protein = Bax, Bad
Bcl-2 has direct action on mitochondria to prevent increased permeability and by effects mediated by interactions with other proteins.
Extra Edge: Annexin V as marker for apoptotic cell membrane having phosphatidylserine on the cell interior.