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Physiology

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Endocrinology

Question
19 out of 50
 

Which of the following is true regarding polycystic ovary disease:



A Low progesterone

B Normal or elevated LH/FSH

C High LH, FSH and estradiol

D Low LH, FSH and estradiol

Ans. B Normal or elevated LH/FSH
  1. POLYCYSTIC OVARIAN DISEASE is the most common cause of ovarian hyper-androgenism.
  2. The salient feature of the disease is the pubertal onset of chronic anovulation and hirsutism. Stein-Leventhal syndrome (Enlarged cystic ovaries, obesity, and amenorrhea) is present in about 50% of women with this disorder but is not required for the diagnosis.
  3. The fundamental abnormality in polycystic ovarian disease is not fully known, but ELEVATED LEVELS OF PLASMA LH lead to enhanced androgen secretion by stromal and thecal cells of the ovary. Q

Polycystic ovary

Disease

Ovarian tumor

Congenital

Adrenal hyperplasia

Urinary17-ketosteroids, plasma

DHEA sulfate

Normal or elevated

Normal

Normal or elevated

Plasma testosterone

Normal or elevated

Much elevated

Normal or elevated

LH/FSH ratio

Normal or elevated

Normal

Normal

Precursors of cortisol biosynthesis:

:Basal

:Following ACTH infusion

Normal

Normal

Normal or elevated

Normal

Normal

Much elevated

Cortisol following overnight

dexamethasone suppression test

Normal

Normal

Normal

Endocrinology Flashcard List

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