Which of the following is not true about immunoglobulins:
|A||Constant region of heavy chains are different in different classes of immunoglobulins|
|B||Variable regions of heavy chains are responsible for difference in characteristics of immunoglobulins|
|C||Light chains are similar in all immunoglobulins|
|D||IgG is predominant immunoglobulin|
a. Antibody molecule consists of two heavy chains and two light chains.
b. Light chains are of two types, kappa and lambda. Each heavy and light chain has a variable and a constant region.
c. Antigen binding site is formed by VH and VL region. Classes of antibodies are based on the constant heavy chain (CH) region. Based on CH region antibodies have five classes (G,A,M,D,E). Biological properties of antibodies depend upon the CH region.
d. Antibody with highest concentration in serum is IgG.10487818