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Central Nervous System

3 out of 9

Which of the following is involved in amyotrophic lateral sclerosis?

A Raphae nucleus

B Lower motor neuron

C Posterior column

D Anterior and posterior column

Ans. B Lower motor neuron
  1. Amyotrophic lateral sclerosis is the most common form of progressive motor neuron disease Q.
  2. The pathology of motor neuron degenerative disorders involve lower motor neurons Q (consisting of anterior horn cells in spinal cord and their brainstem homologues innervating bulbar muscles) and upper or corticospinal motor neurons (emanating from layer 5 of motor cortex to descend via the pyramidal tract to synapse with lower motor neurons, either directly or indirectly via interneurons).