Vocal cords paralysis
Which of the following is precancerous lesion: (DNB Dec 2011)
|A||Pachydermia of larynx|
|C||Keratosis of larynx|
Ref. Read below
Ref. Scotts Brown 7th/ed vol-2 pg-2221; Dhingra 5th/ed pg-323, 6th/ed p 304; Mohan Bansal p 487
• Lichen planus has no malignant potential. . ... Turner 1 Oth/ed p 126
• Papilloma- "The malignant transformation from benign non keratining squamous papilloma to squamous cell carcinoma can occur in children, but is rarely seen" - Current Otolaryngology Znd/ed p 471
• Leukoplakia is a white patch, in which there is epithelial hyperplasia along with atypical cells. It is a premalignant condition.
• Another name for leukoplakia is hyperkeratosis dyskeratosis - Scott's Brown Zth/ed vol-2 p 2221
• Smoking is a predisposing factor, not a premalignant condition.
• In some cases of chronic laryngitis, the laryngeal mucosa becomes dysplastic particularly over true vocal folds and is a premalignant condition. ... Bailey 24th/ed p 765
• Chronic inflammatory conditions of larynx like chronic laryngitis may develop into malignancy. '" Maqboolll th/ed p 359
• Keratosis of larynx/leukoplakia:-
• It is epithelial hyperplasia of the upper surface of oneor both vocal cords.
• Appears as a white plaque or warty growth on cord without affecting its mobility
• Regarded as a precarcerous condition as Ca in situ develops frequently
• T It=stripping of cords