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Medicine

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Hematology

Question
4 out of 11
 

Which of the following is not seen in a chronic case of Sickle cell anemia: (DNB Dec 2010)



A Hepatomegaly

B Pulmonary hypertension

C Cardiomegaly

D Splenomegaly

Ans. D

Splenomegaly

Clinical Features

1. Anemia (Hb 6 –8 gm/dl), reticulocytosis (10 –20%), jaundice, painful swelling of hands and feet.

2. Splenomegaly is not a feature (autosplenectomy occurs Q).

3. Chronic ill – health, renal failure, bone pain necrosis, infections, leg ulcers can result, Pulmonary arterial hypertension

Extra Edge: “Sickle cell anemia is characterized by Hyposplenism due to Autosplenectomy”

Hematology Flashcard List

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