Which of the following is/are true regarding CCK?
|A||Like gastrin, it shows micro- and acroheterogeneity|
|B||Its T/2 is about 5 minutes|
|C||It is secreted by I cells in the upper small intestine|
CCK is formed from its precursor prepro-CCK. The various forms of CCK are :
CCK 58, CCK 39, CCK 33, CCK 12, CCK 8, CCK 4 (the numbers indicate the number of amino acids);
Unlike gastrin, the non-sulphated form of CCK is not found in the tissues.
The CCK secreted in the duodenum and jejunum is mostly CCK 8 and CCK 12.
The enteric and pancreatic nerves contain primarily CCK.
CCK 58 and CCK 8 are found in the brain.