Gram Positive Cocci
Which of the following is caused by Staphylococcus:
a. Ritter’s disease (staphylococcal scalding skin syndrome) is caused by epidermolytic toxin produced by S. aureus. It occurs mostly in young children due to the hematogenous dissemination of exfoliatins EF-A and EF-B from the site of colonization by S.aureus. Exfoliatins have proteolytic action on desmoglein leading to loss of cohesion between keratinocytes.
b. Scarlet fever and erysipelas is caused by S.pyogenes.
c. Pemphigus vegetans is a localized and benign form of pemphigus vulgaris. This is an autoimmune disease due to formation of antibodies against desmoglein leading to loss of cohesion between keratinocytes.