52 out of 91
Which of the following is "hit and run" drug?
Ans. C Reserpine
- Reserpine is an adrenergic neuron blocker, which acts at the membrane of intraneuronal granules that store monoamine (NA, 5-HT, DA. and irreversibly inhibits the active amine transport.
- The monoamine are gradually depleted and degraded by monoamine oxidase. The effects last long after the drug is eliminated (hit and run drug) because tissue catecholamine stores are restored only gradually.