Loading....
Coupon Accepted Successfully!

Microbiology

Open Flashcards

Gram Positive Cocci

Question
57 out of 78
 

Which of the following is true regarding menin-gitis with Streptococcus pneumoniae?



A Cephalosporins are always effective.

B One desires a concentration of antibiotics in the cerebral spinal fluid 10 times the minimal inhibition concentration.

C Penicillin is always effective.

D Resistance is not increasing in Streptococcus pneumoniae.

Ans. B One desires a concentration of antibiotics in the cerebral spinal fluid 10 times the minimal inhibition concentration.

a. Because pneumococci are sensitive to many antimicrobial drugs, early treatment usually results in rapid recovery. Antibody response (host's active immunity) seems to play a diminished role today.

b. Penicillin G is the drug of choice, but 5-10 percent of the isolates in the United States are penicillin resistant (MIC ³ 2 microgram/mL), and 20 percent are moderately resistant (0.1-1 microgram/mL).

c. Resistance to cephalosporins, tetracycline, and erythromycin has been demonstrated, although pneumococci remain susceptible to vancomycin. In reference to penicillin therapy, one rule of thumb is to aim for a concentration of 10 times the MIC in the CSF.

Gram Positive Cocci Flashcard List

78 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)
14)
15)
16)
17)
18)
19)
20)
21)
22)
23)
24)
25)
26)
27)
28)
29)
30)
31)
32)
33)
34)
35)
36)
37)
38)
39)
40)
41)
42)
43)
44)
45)
46)
47)
48)
49)
50)
51)
52)
53)
54)
55)
56)
57)
58)
59)
60)
61)
62)
63)
64)
65)
66)
67)
68)
69)
70)
71)
72)
73)
74)
75)
76)
77)
78)