Which of the following is not true about Nesiritide?
|A||It is BNP analogue|
|B||Used in decompensated CHF|
|D||Causes loss of Na+ in urine|
Nesiritide is a recombinant form of Brain Natriuretic peptide
a. It is a potent vasodilator (arterial and venous) which reduces ventricular filling pressures →↑ CO
b. Also causes diuresis and natriuresis
c. Administered intravenously (bolus followed by infusion)
Use: Acutely decompensated CHF
Adverse effect: Hypotension (may be severe and sustained.