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Medicine

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Kidney

Question
8 out of 21
 

Which of the following is true about CRF?



A   Burr cell                                      

B   Hypersegmentation of neutrophil nucleus

C   Normocytic normochromic anemia             

D   All of the above

Ans. D All of the above

Hematologic. (Fatigue is the commonest symptom which occurs due to anemia).

Table - Causes of Anemia in CKD (Ref. H-18th Edi, P- 2316 Table 280-5)

1. Relative deficiency of erythropoietin

2. Diminished red blood cell survival

3. Bleeding diathesis

4. Iron deficiency

5. Hyperparathyroidism/bone marrow fibrosis

6. Folate or vitamin B12 deficiency

Extra Edge:

A. Anaemia (normochromic, normocytic due to diminished erythropoiesis, shortened RBC survival, and in some cases, blood loss) (S. Fe, TIBC, S. Ferritin all are normal)

B. Poor hemostasis (prolonged bleeding time, lower platelet factor III activity, mild thrombocytopenia and platelet function abnormalities)

C. Leukocyte abnormalities. (P/S reveals Burr cells and hyper segmentation of Neutrophill nucleus)

Extra edge:

Hyper segmentation of Neutrophil nucleus is also seen in

A. Chronic liver disease B. Burns C. microangiopathic hemolytic anemia.

Kidney Flashcard List

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