9 out of 100
Which of the following is cell cycle specific (LQ)
Ans. C Vinblastine
- Vinblastine is a M phase specific vinca alkaloid. It blocks the mitotic spindles and produces metaphase arrest.
- Since it produces an interference with chromosomal segregation it is useful in tumors that are rapidly dividing.
- The drug is used in blood and reproductive cancers. Side effects include nausea, vomiting, myelosupression and bone marrow depression.