Which of the following is used for maintaining heart rate in the intraoperative period? (AIPG 2007)
Esmolol is the drug of choice for maintaining heart rate in the intra operative period. Previously metoprolol was used.
1. Salient points about esmolol:
a. Esmolol is a beta 1 selective antagonist with very short duration of action.
b. It has little if any intrinsic sympathomimetic activity and it lacks membrane stabilizing actions
c. Esmolol is administered IV and is used when beta blockade of short duration is desired or in critically ill patients in whom adverse effects of bradycardia, heart failure, or hypotension may necessitate rapid withdrawl of the drug
d. Halflife of esmolol is 8 minutes
e. It is excreted in urine