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Medicine

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Cardiology

Question
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Which of the following about atherosclerosis is true?



A Intake of unsaturated fatty acid associated with decreased risk

B Thoracic aorta involvement is more severe than abdominal aorta involvement

C Extent of lesion in veins is same as that in arteries

D Hypercholesterolemia does not always increase the risk of atherosclerosis perse

Ans. A

Intake of unsaturated fatty acid associated with decreased risk

1. Atherosclerosis is a condition in which an artery wall thickens as a result of the accumulation of fatty materials such as cholesterol.

2. It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries, caused largely by the accumulation of macrophage white blood cells and promoted by low-density lipoproteins without adequate removal of fats and cholesterol from the macrophages by functional high density lipoproteins (HDL),

3. It is commonly referred to as a hardening or furring of the arteries.

4. It is caused by the formation of multiple plaques within the arteries.

The atheromatous plaque is divided into three distinct components:

1. The atheroma which is the nodular accumulation of a soft, flaky, yellowish material at the center of large plaques, composed of macrophages nearest the lumen of the artery

2. Underlying areas of cholesterol crystals

3. Calcification at the outer base of older/more advanced lesions.

Cardiology Flashcard List

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