Autocoids (Histamine and Serotonin)
Which of the following drug is associated with highest cardiac mortality? (AIIMS May 2012)
Angiotensin receptor blockers (like losartan) and beta-blockers (like metoprolol) are cardioprotective in congestive heart failure. These decrease the mortality.
Nicorandil is a potassium channel opener used in angina. It is cardioprotective by causing ischemic pre-conditiong
Rofecoxib is a selective COX-2 inhibitor that was withdrawn due to increased risk of myocardial infarction.