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Medicine

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Neurology

Question
11 out of 23
 

Which of the following drug is used in the treatment of Alzheimer disease?



A Rivastigmine
B Galantamine

C Memantine
D All of the above

Ans. D

All of the above

TREATMENT –

Donepezil- drug of choice

Tacrine-(S/E- hepatotoxicity)

MAO – Inhibition of cholinesterase with resulting increase in cerebral levels of acetylcholine

Recent Advances: Newer drugs

1). Rivastigmine

2). Galantamine

3). Memantine

4). Huperzine A

Extra Edge: HUPERIZINE-A (This drug is not given in Harison 18th ed also !!!)

1). Huperzine A is a naturally occurring alkaloid compound found in the plant Huperzia serrata.

2). Huperzine A is also an Acetylcholinesterase inhibitor, which has a mechanism of action similar to donepezil, rivastigmine, and galantamine. A pro-drug form of Huperzine .

Neurology Flashcard List

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