Loading....
Coupon Accepted Successfully!

Medicine

Open Flashcards

Respiratory

Question
12 out of 13
 

Which of the following drug is used in refractory asthma? (PNQ)



A Omalizumab
B Infliximab

C Alemtuzumab
D Eculizumab

Ans. A

Omalizumab

Recent Advances: (Ref. Hari-18th ed. Pg- 2113)

Refractory Asthma: Treatment

Definition: Asthma which is difficult to control is called as refractory asthma.

1). Low doses of theophylline may be helpful in some patients, and theophylline withdrawal has been found to worsen many patients.

2). Most of these patients require maintenance treatment with oral corticosteroids.

3). Steroid-sparing therapies are rarely effective.

4). Omalizumab (Anti-TNF therapy) is effective, particularly when there are frequent exacerbations.

5). A few patients may benefit from infusions of beta 2-agonists.

Extra edge: Uses of Various Monoclonal antibodies

Main category

Type

Application

Anti- inflammatory

Infliximab

§ Rheumatoid Arthritis

§ Crohn's disease

§ Ulcerative Colitis

Adalimumab

§ Rheumatoid Arthritis

§ Crohn's disease

§ Ulcerative Colitis

Etanercept

§ Rheumatoid Arthritis

Basiliximab

§ Acute rejection of kidney transplants

Daclizumab

§ Acute rejection of kidney transplants

Omalizumab

§ Moderate-to-severe allergic asthma

Anti-cancer

Gemtuzumab

§ Relapsed acute myeloid leukaemia

Alemtuzumab

§ B cell leukemia

Rituximab

§ Non-Hodgkin's Lymphoma, CLL

Trastuzumab

§ Breast cancer with HER2/neu overexpression

Nimotuzumab

§ Approved in squamous cell carcinomas, Glioma

Cetuximab

§ Squamous Cell Carcinomas, colorectal carcinoma

Bevacizumab

§ Anti-angiogenic cancer therapy

Other

Palivizumab

§ RSV infections in children

Abciximab

§ PREVENT coagulation in coronary angioplasty

Eculizumab

§ PNH

Respiratory Flashcard List

13 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
13)