Which of the following statements regarding multiple epiphyseal dysplasia is correct?
|A||Inheritance is usually autosomal recessive|
|B||The diagnosis is usually made in infancy|
|C||Vertebral involvement is prominent|
|D||Misdiagnosis as Legg-Calve-Perthes disease is common|
Misdiagnosis as Legg-Calve-Perthes disease is common
a. Multiple epiphyseal dysplasia is an autosomal dominant condition characterized by irregularity of the epiphyses.
b. The condition is not obvious in infancy; as a result, the diagnosis may not be made until early adolescence. In contrast to spondyloepiphyseal dysplasia, vertebral involvement is not seen.
c. As involvement is usually bilateral, differentiation from Legg-Calve-Perthes disease is a common problem. There is no evidence that orthotic devices improve the outcome.