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Pharmacology

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Diuretics

Question
16 out of 31
 

Which of the following diuretic does not require its presence in the tubular lumen for its pharmacological effects? (AIIMS Nov 2009)



A Thiazide diuretics.

B Loop diuretics

C Carbonic anhydrase inhibitors

D Aldosterone antagonists

Ans. D Aldosterone antagonists

Most of the diuretics act from the luminal side of membrane in the nephron. Aldosterone antagonists (spironolactone) do not act through luminal side rather they act from basolateral side of the membrane. So these agents do not require access to the tubular lumen

Diuretics Flashcard List

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