Which of the following causes persistent leucopenia? (AIIMS Nov 2011)
Carmustine causes persistent neutropenia with a delayed nadir.
Carmustine of BCNU is a mustard gas-related α-chloronitrosourea compound used as an alkylating agent in chemotherapy.
It is used in the treatment of several types of brain cancer (including glioma, glioblastoma multiforme, medulloblastome and astrocytoma., multiple myeloma and lymphoma (Hodgkin’s and non-Hodgkin).