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Medical and Surgical Complications in Pregnancy

Question
35 out of 45
 

Which of the following hepatitis virus have significant perinatal transmission (DNB June 2011)



A Hepatitis-E virus
B Hepatitis-C virus

C Hepatitis-B virus
D Hepatitis-A virus

Ans. B

Hepatitis -B

1. Hepatitis -B

a. The risk of chronic hepatitis B infection in neonate who does not receive immunoprophylaxis and vaccination is 40%

b. Vertical transmission is 10% in mother with negative HBe Ag

c. When the women are infected during the 2nd and 3rd trimester the neonatal infection is 6% and 67% respectively and virtually all are infected in the perinatal period

2. Hepatitis - C

a. A marked variation is noted in vertical transmission rates of HCV is - 0 36%

b. In hepatitis C VIR positive, HIV negative mothers, without history of IV drugs abuse or transfusion exposure, the risk of HCV vertical transmission is 0-18%

c. In patients who are HIV negative with ongoing IV drug abuse or blood transfusion during pregnancy - risk - 23% . HIV positive mothers vertical transmission rates - 6 - 36%

3. Hepatitis - E

a. First trimester = 8.80%

b. Second trimester = 19.40%

c. Third trimester = 18.60% [Hepatic failure was noticed]

i. Most common cause of epidemic viral hepatitis.

ii. Acute hepatitis cases were 87% and hepatic failure occurred in 58%

Hepatitis A - in non teratogenic and risk of fetal transmission is negligible but vertical transmission at the time of delivery was documented as a cause of outbreak of hepatitis A, in a neonatal care unit. .

Medical and Surgical Complications in Pregnancy Flashcard List

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