Gram Positive Bacilli
Which of the following statement about botulism is not true: (AIIMS Nov 2010)
|A||Pin point pupils is characteristic|
|B||Toxin blocks the production or release of acetylcholine at synapses|
|C||Spores are highly resistant to heat|
|D||Death occurs usually due to respiratory failure|
a. In botulism pupils are dilated rather than pinpoint.
b. Spores of Cl.botulinum can resist boiling for several hours and destroyed only at 121 C for 10 min.
c. Botulinum toxin blocks the release of acetylcholine at the neuromuscular junction and parasympathetic postganglionic terminals, by breaking down proteins at the presynaptic terminals responsible for the fusion of Ach vesicles with neuronal cell membrane.
d. Death occurs due to respiratory paralysis.