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Reproductive Physiology, Endocrinology, and Infertility

Question
43 out of 56
 

Which of the following treatment for menorrhagia is not supported by evidence? (AIIMS May 2010)



A Ethamsylate

B Tranexaminic acid

C OCP

D Progesterone therapy on days 5 –25

Ans. A
Ethamsylate

1. Various options are available for medical management of menorrhagia.

2. These include:

a. O.C. pills

b. Progesterone’s (oral/DMPA/MIRENA)

c. Antifibrinolytic agents (Tranexamic acid)

d. Danazol & GnRH analogues (very rarely used)

e. NSAIDS

f. Ethamsylate (Capillary stabilizers)

3. All these medications can control the menorrhagia

4. In various clinical trials (evidence based medicine) O.C Pills, Tranexamic acid & cyclical progesterone from day 5-25 of menstrual cycle have been effective in menorrhagiA.

5. The efficacy of ethamsylate in management of menorrhagia has not been proven in clinical trials even though it decreases the blood loss & is also used in clinical practice for menorrhagiA.

Reproductive Physiology, Endocrinology, and Infertility Flashcard List

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