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Pharmacology

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Blood

Question
44 out of 45
 

Which of the following does not act on IIb/IIIa receptors? (LQ)



A Abciximab
B Eptifibatide

C Tirofiban
D Clopidogrel

Ans. D Clopidogrel

Clopidogrel is a congener of ticlopidine with similar mechanism of action, ability to inhibit platelet function and therapeutic efficacy but is better tolerated and has a lower frequency of neutropenia and thrombocytopenia.

Other antiplatelet drugs in use are:

Ticlopidine (acts by inhibting ADP induced platelet aggregation)

Dipyridamole (Inhibitor of adenosine uptake and cGMP phosphodiesterase activity)

Cilostazol (vasodilator and inhibitor of platelets aggregation; used in intermittent claudication).

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