Which of the following are true about therapy for tuberculosis:
|A||"Flu-like syndrome is usually seen in people taking rifampicin on daily basis|
|B||Ethambutol accumulates in renal failure|
|C||Hyperuricemia is a recognized side effect of pyrazinamide|
|D||Red green color impairment is an early sign of ethambutol induced optic neuritis|
a. Intermittent use of rifampicin may increase the chance of a patient developing the "flu-like" syndrome, as well as acute hemolysis or renal failure.
b. These reactions are thought to be immunologically mediated and intermittent use should be limited to those conditions, such as leprosy, in which its safety and efficacy have been established.