Which of the following processes generates the most ATP?
|A||Citric acid cycle|
|B||Fatty acid oxidation|
|D||Pentose phosphate pathway|
a. The pentose phosphate pathway does not generate any ATP but instead forms NADPH and ribose phosphate. Glycolysis produces a net two ATP molecules per glucose.
b. The citric acid cycle produces a net 12 ATP per turn of the cycle Fatty acid oxidation of palmitate results in a total of 129 ATP.
c. Electron transport in the respiratory chain results in 5 ATP for each of the first 7 acetyl CoA produced by the oxidation of palmitate for a total of 35 ATE Each of the 8 acetyl- CoA molecules produced from palmitate results in 12 ATP from the citric acid cycle for 96 total ATE
d. This gives a total of 131 AIP per palmitate oxidized, minus 2 ATP for the initial activation of palmitate for a grand total of 129 ATP per palmitate.