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Physiology

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Question
8 out of 33
 

Which of the following statement is true for high altitude pulmonary edema?



A It reduces after exercise.

B It occurs only in acclimatized individuals.

C It is associated with pulmonary hypertension.

D It is more likely to occur above the height of 300 m.

Ans. D It is associated with pulmonary hypertension.

I. Small percentage of people who ascend rapidly to high altitudes become acutely sick and can die if not given oxygen or removed to a low altitude.

II. The sickness begins from a few hours up to about 2 days after ascent. It is called acute mountain sickness and more common in Unacclimatized individuals, after exercise and if ascend is done without rest.

III. Acute mountain sickness presents with acute pulmonary edema.

IV. The severe hypoxia causes the pulmonary arterioles to constrict potently, but the constriction is much greater in some parts of the lungs than in other parts, so that more and more of the pulmonary blood flow is forced through fewer and fewer still unconstricted pulmonary vessels.

V. The capillary pressure in these areas of the lungs becomes especially high (so associated with pulmonary hypertension) and local edema occurs. Extension of the process to progressively more areas of the lungs leads to spreading pulmonary edema and severe pulmonary dysfunction that can be lethal. Allowing the person to breathe oxygen usually reverses the process within hours. So high-altitude pulmonary edema is a patchy edema of the lungs that is related to the marked pulmonary hypertension that develops at high altitude.

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