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Medicine

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Hematology

Question
20 out of 34
 

Which of these is true regarding CML: (AIIMS May 10)



A Size of splenomegaly indicates prognosis

B Phagocytic activity of WBC is reduced

C Sudan black stain is specific for myeloblast

D Myeloblast, granuloblast and lymphoblast become Philadelphia chromosome negative following remission

Ans. A

Size of splenomegaly indicates prognosis

Size of splenomegaly indicates prognosis…cytogenetic changes e.g. Philadelphia chromosome persist in bone marrow cells in CML remission.

Sokal index (Prognosis in CML)

1. % of circulating blast cells

2. Spleen size

3. Platelet count

4. Age

5. Cytogenetic clonal evaluation

Extra Edge: Size of splenomegaly indicates prognosis

Hematology Flashcard List

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