Which one of the following statements concerning glycolysis is correct?
|A||The conversion of glucose to lactate requires the presence of oxygen.|
|B||Hexokinase is important in hepatic glucose metabolism only in the absorptive period following consumption of a carbohydrate-containing meal.|
|C||Fructose 2,6-bisphosphate is a potent inhibitor of phosphofructokinase.|
|D||The regulated reactions are also the irreversible reactions.|
a. Hexokinase, phosphofructokinase, and pyruvate kinase are all irreversible and are the regulated steps in glycolysis.
b. The conversion of glucose to lactate (anaerobic glycolysis) is a process that does not involve a net oxidation or reduction and, thus, oxygen is not required.
c. Glucokinase (not hexokinase) is important in hepatic glucose metabolism only in the absorptive period following consumption of a carbohydrate-containing meal.
d. Fructose 2,6-bisphosphate is a potent activator (not inhibitor) of phosphofructokinase. The conversion of glucose to lactate yields two ATP but no net production of NADH.