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Biochemistry

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Vitamins, Harmones and Hemoglobin

Question
8 out of 30
 

Which one of the following statements about glucagon is correct?



A High levels of blood glucose increase the release of glucagon from the a cells of the pancreas.

B Glucagon levels decrease following ingestion of a protein-rich meal.

C Glucagon increases the intracellular levels of cAMP in liver cells, causing an increase in glycogen breakdown.

D Glucagon is the only hormone important in combating hypoglycemia.

Ans. C Glucagon increases the intracellular levels of cAMP in liver cells, causing an increase in glycogen breakdown.

a. The cAMP cascade initiated by glucagon causes the liver to degrade glycogen, releasing glucose to the blood. High levels of blood glucose decrease the release of glucagon from the α cells of the pancreas.

b. Glucagon levels increase following ingestion of a protein-rich meal. In addition to glucagon, epinephrine and cortisol are also important in increasing glucose production in hypoglycemia. Glucagon increases the formation of ketone bodies by the liver.

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