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Surgery

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General Surgery

Question
11 out of 142
 

Which statement regarding transmission of viral illness through homologous blood transfusion is true?



A The most common viral agent transmitted via blood transfusion is HIV

B Blood is routinely tested for CMV because CMV infection is often fatal

C The most frequent infectious complication of blood transfusion continues to be viral meningitis

D Up to 10% of those who develop posttransfusion hepatitis will develop cirrhosis or hepatoma or both.

Ans. D Up to 10% of those who develop posttransfusion hepatitis will develop cirrhosis or hepatoma or both. (REF. SABISTON SURGERY 18TH EDITION PG 423)

Hepatitis

a. Transmission of the infectious agents for hepatitis is among the most serious risks associated with blood transfusion.

b. Transfusion-associated HBV infection occurs in approximately 1 in 30,000 to 250,000 units transfused. The risk of transmitting HCV is now as low as 1 in 1 million.

c. Symptoms develop in approximately half the blood recipients who contract HBV infection. In approximately half the patients who contract post-transfusion HCV infection, a chronic form of the disease develops.

Human Immunodeficiency Virus

The the risk of HIV transmission is estimated to be as low as 1 in 2 million units.

Human T-Cell Leukemia Virus

a. Transmission of the virus, especially to immunocompromised patients, may cause illnesses such as T-cell leukemia, spastic paraparesis, and myelopathy.

b. The risk of HTLV-I and HTLV-II transmission is estimated to be 1 in 641,000 units.

Herpesviruses

a. CMV infection is endemic, so routine screening is not performed in the United States.

b. About 20% of blood donors are infected with CMV by 20 years of age, and approximately 70% are infected by the age of 70

c. Human herpesvirus 8 causes Kaposi's sarcoma and lymphoma in patients with acquired immunodeficiency syndrome and other immunosuppressed states such as transplantation.

General Surgery Flashcard List

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