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Pathology

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Female Genital Tract

Question
5 out of 15
 

With regard to the malignant behavior of leiomyosarcoma, the most important criterion is: (LQ)



A Blood vessel penetration by tumor cells

B Tumor cells in lymphatic channels

C Lymphocyte infiltration

D The number of mitoses per high power field

Ans. D The number of mitoses per high power field

The most important criterion for distinction of leiomyosarcoma from leiomyoma (malignant transformation) is the number of mitoses Present.

Ten high power fields (hpf) are examined. If > 10 mitoses are seen it signifies malignancy lf cellular atypia is also present >5 mitoses are enough to make a diagnosis of leiomyosarcoma.

Female Genital Tract Flashcard List

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