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Medicine

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Kidney

Question
13 out of 14
 

ln renal cell carcinoma which is not associated (AIIMS May 2011)



A Polycythemia
B Amyloidosis

C Cushing syndrome
D Malignant hypertension

Ans. C Cushing syndrome

a. In renal cell carcinoma, the presenting signs and symptoms triad

i. Hematuria, ii. Abdominal pain, iii. A flank or abdominal mass.

b. Other symptoms are fever, weight loss, anemia, and a varicocele

c. The tumor can also be found incidentally on a radiograph. Widespread use of radiologic cross-sectional imaging procedures (CT, ultrasound, MRI) contributes to earlier detection.

d. Paraneoplastic syndromes associated with RCC

i. Erythrocytosis ii. Hypercalcemia iii. Nonmetastatic hepatic dysfunction (Stauffer syndrome)

e. Acquired dysfibrinogenemia.

f. Erythrocytosis is noted at presentation in only about 3% of patients. Anemia, a sign of advanced disease, is more common.

Signs and Symptoms in Patients with Renal Cell Cancer

Presenting Sign or Symptom

1. Classic triad: hematuria, flank pain, flank mass

2. Hematuria , Flank pain, Palpable mass

3. Weight loss, Anemia, Fever

4. Hypertension

5. Abnormal liver function, Hypercalcemia, Erythrocytosis

6. Neuromyopathy, Amyloidosis

7. Increased ESR

Kidney Flashcard List

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