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One type of vesicle that buds from the Golgi is the lysosome. These organelles function in intracellular digestion. They contain enzymes that break down polysaccharides, proteins, nucleic acids and some lipids. Lysosomes can fuse with endocytotic vesicles that have formed from the cell membrane (see Chapter 11). These vesicles contain molecules, and sometimes cells, obtained from outside the cell. Once the lysosome fuses with an endocytotic vesicle, the digestive enzymes will break down the substances taken into the cell.
Sometimes the lysosomes digest the cell itself.
For example, the tail on a tadpole is digested by lysosomes as part of the normal programmed development of a frog.


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