80 year old, asymptomatic man present with a Total Leucocyte Count of 1 lakh, with 80% lymphocytes and 20% PMC's. What is the most probable diagnosis? (AI 2010, AI 2012)
This is the most common variety of leukaemia, occurs in elderly person. CLL constitutes 25% of all leukaemias. Transformation into ALL is not a feature
Clinical Features (Mostly asymptomatic)
Weight loss stage, infection, bleeding, enlarged rubbery nontender nodes, hepatosplenomegaly.
Stages of CLL