A diabetic patient is reportedly brought to hospital in coma. Her relatives give a history of a black nasal discharge before the patient went into coma. On examination, there is proptosis and chemosis of her left eye. What could be the identity of the fungus isolated from the sinus aspirate. (AIPG 2012)
a. This is suggestive of rhinocerebral disease caused by zygomycetes. The infection spreads from nasal mucosa to sinuses to extend to the orbit and brain leading to vessel invasion and infarction
b. The patient manifests with nasal discharge, facial pain, headache, periorbital cellulitis, loss of vision, proptosis.
c. Risk factors to this disease are-
e. Iron overload states
f. Prolonged neutropenia
g. Leukemia, lymphoma